Setmelanotide
$240.00
Imcivree weight loss (setmelanotide) is an FDA-approved prescription injection for children and adults with obesity caused by rare genetic conditions like POMC, PCSK1, LEPR deficiency, and Bardet-Biedl syndrome. It works by activating brain receptors that control appetite and energy use, helping reduce hunger and support weight loss. Imcivree is not for general obesity and is available only with a prescription.
Description
Imcivree Weight Loss (Setmelanotide)
What is Imcivree (setmelanotide)?
Imcivree weight loss (setmelanotide) is an FDA-approved prescription injection for long-term weight management in people 6 years and older with rare genetic conditions that cause obesity. It targets the brain pathways that regulate appetite and metabolism, helping reduce hunger and support weight loss.
What is Imcivree weight loss (setmelanotide) used for?
Imcivree is prescribed for weight loss in people with obesity caused by:
How Imcivree weight loss (setmelanotide) works
Imcivree is a melanocortin receptor agonist. It activates melanocortin-4 receptors in the brain, which regulate hunger and energy use. By reducing appetite and boosting calorie burning, Imcivree helps patients achieve and maintain weight loss.
Typical dosing for Imcivree
- Adults and children 12 years and older: Start with 2 mg (0.2 mL) injected under the skin once daily for 2 weeks
- Children 6 to 11 years: Start with 1 mg (0.1 mL) once daily for 2 weeks
- Target dose: 3 mg (0.3 mL) injected once daily
- Dose may be adjusted for people with kidney problems
Common side effects
- Redness, pain, or swelling at the injection site
- Nausea, vomiting, diarrhea
- Headache
- Stomach pain or back pain
- Fatigue
- Skin darkening (hyperpigmentation)
- Depression or mood changes
Risks and warnings for Imcivree (setmelanotide)
Some risks require close monitoring during treatment.
Sexual function problems
- Reports of unplanned erections in males and unwanted sexual arousal in females
- Erections lasting longer than 4 hours need immediate care to prevent permanent damage
Depression and suicidal thoughts
- May cause or worsen depression or suicidal thoughts
- Risk is higher if you have a history of mental health conditions
- Report mood changes or suicidal thoughts immediately
Allergic reactions
- Rare but possible within hours of injection
- Symptoms include swelling, throat tightening, or breathing difficulty
- Emergency medical care is required if these occur
Skin darkening
- Causes moles or skin patches to darken
- Typically improves after treatment stops
- Regular skin checks are required
Risks in newborns and infants
- Contains benzyl alcohol, which has been linked to life-threatening reactions in newborns, including “gasping syndrome”
- Not safe for infants
Drug facts
- Brand name: Imcivree
- Generic name: Setmelanotide
- Class: Melanocortin receptor agonist
- Status: Prescription only
- Generic availability: None
Where to buy Imcivree weight loss (setmelanotide)
Imcivree is available only with a prescription. The retail price is about $35,000 per month, but discounts can lower the cost to around $32,000. Compare savings and pharmacy options on GoodRx.
Frequently Asked Questions about Imcivree Weight Loss (Setmelanotide)
How long does it take to see results with Imcivree?
Clinical studies showed weight loss within the first few months of treatment, with continued improvement over time. Results vary based on the genetic condition being treated.
Is Imcivree safe for children?
Yes. Imcivree is approved for children 6 years and older with obesity caused by eligible genetic conditions. It is not safe for infants or newborns.
What happens if I miss a dose of Imcivree?
If you miss a dose, take it as soon as you remember. If it’s almost time for your next dose, skip the missed dose and return to your regular schedule. Do not take extra doses.
How is Imcivree stored?
Keep Imcivree refrigerated between 36°F and 46°F (2°C and 8°C). Do not freeze. Store in the original carton to protect it from light.
Who should not take Imcivree?
- Infants and newborns
- People with a history of severe allergic reaction to setmelanotide or its ingredients
- People with untreated mental health conditions should use caution
Is there a generic version of Imcivree?
No. Imcivree is only available as a brand-name medication.
Elio Milton –
Finally found something that works for my condition. The service was smooth, delivery was prompt, and I’ve already started noticing appetite control. Really grateful for this treatment.
Maela –
I’ve struggled for years with my weight due to a rare genetic condition. Since starting Setmelanotide, my hunger is more manageable. Delivery was fast and support has been amazing!
Kairo –
The product arrived on time, safely packaged, and with all the guidance I needed. It’s been a game-changer in managing my hunger levels. Can’t thank the team enough.
Amryn –
Setmelanotide has genuinely changed my day-to-day life. Appetite is finally under control. Excellent service and consistent delivery make this a stress-free process.
Bêla Chan –
Efficient and reliable service. Got the medication right on schedule, and it’s making a clear difference. I feel more in control and supported throughout.